教員紹介

李 宜融 リー・イユウ
Lee IJung

所属・肩書

漢方薬学科/生薬・薬用資源学研究室(教授)

最終学歴

日本大学大学院生物資源科学研究科修了

中国広州中医薬大学熱帯医学研究所研究生修了

取得学位

生物資源科学博士(日本大学)

医学博士(中国広州中医薬大学

所属学会

日本生薬学会、日本薬学会、台湾抗老化保健学会、中華民国中医予防及び康復医薬会、台湾植物学会

現在の専門分野

生薬学、薬用植物学、生物資源学

現在の研究課題

●生薬の基原・資源に関する研究
●有用植物の資源調査及び応用検討
●生薬標本の管理・保存

主要研究業績

●薬用植物の形態・組織・遺伝子に関する鑑別研究
●台湾中薬典の生薬の基原鑑別研究
●植物資源の地域調査及び応用考察
●中国古典文献の科学的解明研究
●生薬標本館の管理

最近の研究業績

1.Chemical constituents of the plant Antidesma ghaesmbilla. R L. Gonzales, CC Shen, IJ Lee, MJ Don, C Y. Ragasa, Chemistry of Natural Compounds; vol.55, No.2, March. (2019)

2.Giseng-plus-Bai-Hu-Tang ameliorates diet-induced obesity, hepatic steatosis and insulin resistance in mice. HF Lu, YH Lai, HC Huang, IJ Lee, LC Lin, HK Liu, HH Tien and C Huang. Joumal of Ginseng Research; S1226-8453(18)30128-3. (2018)

3.Purification, structural elucidation, and anti-inflammatory activity of xylosyl galactofucan from Armillariella mellea. Chia-Chuan Chang, Jing-Jy Cheng, I-Jung Lee, Mei-Kuang Lu. International Journal of Biological Macromolecules; 114; 584-591. (2018)

4.Berberine activates aryl hydrocarbon receptor but suppress CYP1A1 induction through miR-21-3p stimulation in MCF-7 breast cancer cells. Lo Sheng-Nan, Wang Chun-Wei, Chen Yueh-Shieh, Wu Tian-Shung, Li Lih-Ann, Lee I-Jung, Ueng Yune-Fang. Molecules. 22, 1847; doi: 10.3390 / molecules 22111847. (2017)

5.Morphological and chemical analyses of Eriocauli Flos sold in Taiwan markets. I-Jung Lee, Cheng-Pei Chung, Shu-Jen Chang, Yun-Lian Lin. Journal of Food and Drug Analysis.; Journal of Food and Drug Analysis; 25; 939-945. (2017)

6.Muraoka O. Quantitative Determination of Alkaloids in Lotus Flower (Flower Buds of Nelumbo nucifera) and Their Melanogenesis Inhibitory Activity. Morikawa T, Kitagawa N, Tanabe G, Ninomiya K, Okugawa S, Motai C, Kamei I, Yoshikawa M, Lee IJ. Molecules. 21(7), 930; doi: 10.3390/molecules 21070930. (2016)

7.Flavone glycosides from commercially available Lophatheri Herba and their chromatographic fingerprinting and quantitation. Jyun-Siang Fan, I-Jung Lee, Yun-Lian Lin. Journal of Food and Drug Analysis; 23, 821-827. (2015)

8.Bai-Hu-Jia-Ren-Shen-Tang decoction reduces fatty liver by activating AMP-activated protein kinase in vitro and in viro. Hui-Kang Liu, Tzu-Min Hung, Hsiu-Chen Huang, I-Jung Lee, Chia-Chuan Chang, Jing-Jy Cheng, Lie-Chwen Lin, and Cheng Huang. Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2015/651734 (2015)

9.Effects of aqueous extract of Ruta graveolens and its ingredients on cytochrome P450, UDP-glucuronosyltransferase, and Q1 NAD(P)H-quinone oxidoreductase in mice. Yune-Fang Ueng, Chien-Chih Chen, Yu-Ling Huang, I-Jung Lee, Chul-Ho Yun, Yu-Hsuan Chen, Chiung-Chiao Huang. Journal of Food and Drug Analysis, 23, 516-528. (2015)

10.The Weights in Ben Cao Jing Ji Zhu (Dun Huang Version) and the Volume of a Fang Cun Bi (One Cun Square Spoon): Weights and Measures in the Period when the Shan Han Lun was Written. Tsukasa Fueki, Takanori Matsuoka, Toshiaki Makino, Takao Namiki, Masashi Beppu, Hidetoshi Yamaguchi, Hideyuki Nakata, Kenshu Rai, Keisuke Hagihara, Koichiro Tanaka, Kazuhiko Nagasaka, Takao Sunaga, I-Jung Lee, Kenkichi Okada, Yusen Iwai, Kazuhiro Makizum.; Kampo Medicine, Vol.65 No.1, 38-45. (2014)

11.Glycyrrhetinic acid suppressed NF-#B activation in TNF-#-induced hepatocytes. Hong-Jhang Chen, Shih-Pei Kang, I-Jung Lee, and Yun-Lian Lin. Journal of Agricultural and Food Chemistry, 62 (3), 618–625 (2014)

12.Scutellariae radix suppresses LPS-induced liver endothelial cell activation and inhibits hepatic stellate cell migration. Chen HJ, Liang TM, Lee IJ, Huang YT, Lin YL.; Journal of Ethnopharmacology, Vol.150. 835-842. (2013)

13.Quantitative analysis of catechin, flavonoid, and saponin constituents in “tea flower”, the flower buds of Camellia sinensis, from different regions in Taiwan. Toshio Morikawa, I-Jung Lee, Shuhei Okaugawa, Sohachiro Miyake, Yoshinobu Miki, Kiyofumi Ninomiya, Kazuki Iwasa, Niichiro Kitagawa, Masayuki Yoshikawa and Osamu Muraoka. Natural Product Communications, Vol.8, No.11, 1553-1557. (2013)

14.The Effects of the Edible Rhubarb Extracts on Rat-Gonarthrosis. Wang Tao, Koichiro Komai, Takayuki Shibamoto, Munekazu Iinuma, Yoshio Kokusenya, Masanori Morimoto, I-Jung Lee, Shoichi Harima and Naritada Fujiki. Journal of New Remedies & Clinics, Vol.62, No.4. 267-273. (2013)

15.Investigation of Two Species of (Aatragalus membranaceus and Hedysarum polybotrys) by HPLC, ITS, Microscopic Morphology and Antioxidant Activities. IJung Lee, Pin-Chieh Huang, Li-Jie Zhang, Chia-Ching Liaw, Ming-Ren Lin, Chia-Jung Yu, Chung-I Huang and Yao-Haur Kuo. Journal of Food and Drug Analysis, Vol. 20, No. 3, 603-610. (2012)

16.Determination of longistylin A and longistylin C in Cajanus cajan. Wang Dawu, Xiao Minxun, Li Yirong, Shen Xiaoling, Lu Yuanyuan, Liu Kanglun, Li Zhenghong, Hu Yingjie. China Journal of Chinese Materia Medica, 2011; Vol. 36, Issue 19, 2680-2683. (2011)

17.Nanoparticles prepared from the water extract of Gusuibu (Drynaria fortunei J. Sm.) protects osteoblasts against insults and promotes cell maturation. Chung-King Hsu, Mei-Hsiu Liao, Yu-Tyng Tai, Shing-Hwa Liu, Keng-Liang Ou, Hsu-Wei Fang, I-Jung Lee, Ruei-Ming Chen. International Journal of Nanomedicine, 6, 1405-1413. (2011)

18.Deciphering the neuroprotective mechanisms of Bu-yang Huan-wu decoction by an integrative neurofunctional and genomic approach in ischemic stroke mice. Wang HW, Liou KT, Wang YH, Lu CK, Lee JI, Huang ST, Tsai YH, Cheng YC, Lin HJ, Shen YC. Journal of Ethnopharmacology. Vol. 138, 22-33. (2011)

19.Cytotoxic Hexacyclic Triterpene Acids from Euscaphis japonica. Jing-Jy Cheng, Li-Jie Zhang, Hui-Ling Cheng, Chun-Tang Chiou, I-Jung Lee, and Yao-Haur Kuo. Journal of Natural Products., 1655-1658. (2010)

20.Review on phytochemical study of Asteraceae in Taiwan. Yun-Lian Lin, Chia-Chuan Chang, I-Jung Lee. Journal of Chinese Medicine 19(3,4): 135-149, (2008)

21.生薬の血流増加作業に関する研究(Ⅰ); 李 宜融,渡邊 智,佐竹元吉;医薬品研究No.38,Vol.6, 267-276 (2007)

受賞

2004年日本常寿科学振興財団奨励賞

最近の学会発表

1.Influence of water properties on the contents of aconitine-type diester alkaloids in the decoctions of unprocessed aconite root. Tsukasa Fueki, Koichiro Tanaka, Koki Chiba, Takao Namiki, I-Jung Lee, Toshiaki Makino. The 19th International Congress of Oriental Medicine. (2018.11.24-26. Taipei, Taiwan)

2.薬用植物からのパクチー考察、李宜融、第2回パクチーアカデミー協会学術会議。(2018.8.18. 東京)

3.Eriocauli Flos Sold in Taiwan Herbal Markets by Morphological and Chemical Analyses. IJ. Lee, Y. M. Chao, W. H. Hsu, Y. L. Lin. The 32th International Symposium on Natural Products. (2017.10.13-14. Taichung, Taiwan)

4.Survey of Commercially Available Eriocauli Flos in Taiwan Area. I-Jung Lee, Yen-Ming Chao, Yun-Lian Lin. The 31th Symposium on Natural Products. (2017.10.21-22. Kaohsiung, Taiwan.)

5.四神湯を起源としたエキス剤による体臭成分の消臭作用に関する研究、後藤洋子, 小松千紘, 作田圭亮, 李宜融, 佐久間克也. 日本生薬学会第62回年会. (2015.9.11-12. 岐阜)

6.Flavone Glycosides from Commercial Available Lophatheri Herba in Taiwan and Their Quantitative Determinations. J. S Fan, IJ. Lee, Y. L. Lin. The 17th International Congress of Oriental Medicine. (2014.11. 1-3, Taipei, Taiwan.)

7.Anti-inflammatory Flavonoids and Lactams of Adlay Bran、Hong-Jhang Chen, Cheng-Pei Chung, I-Jung Lee,  Wenchang Chiang, Yun-Lian Lin. 日本薬学会第132年回(2012.3.28-30. 札幌)

8.メディシナルフラワー研究: 蓮花 (Nelumbo nucifera, 花部) のメラニン生成抑制成分、吉川雅之,横田奈美,中村誠宏,中嶋聡一,宮内美絵子,十文字 悦子, 前田 小百合, 松田久司,李 宜融,村岡 修. 日本薬学会第131年回(2011.3.28-30. 静岡)

9.台湾産茶花(チャ,Camellia sinensis, 花部)成分と品質評価Constituents from flower buds of Camellia sinensis in Taiwan and quality evaluation.、李 宜融,中村誠宏,森川敏生,三宅 荘八郎,岡本将揮,松田久司,村岡 修,吉川雅之.日本薬学会第130年回(2010.3.28-30.岡山)

10.丹参の成分Salvianolic acid Aにおけるマウスの肝臓星状細胞での抗酸化作用、蔡明桂,李宜融,黄怡超,林雲蓮. 日本薬学会第128年回(2008.3.26-28. 横浜)

11.キハダの分類について、Identification of Phellodendron species by the internal transcribed spacer of ribosomal DNA、李 宜融,邱 淑嬌,顔 瑞宏,李 連滋,呉 天賞. 日本薬学会第127年回(2007.3.28-30. 富山)

入試情報 ADMISSION